Pasteur's Research Background Hello, my name is Tokio Oka, and I'd like to talk about Louis Pasteur and his work to create the Rabies Vaccine. Rabies has existed since 3700 years ago. Even now 50,000 people die each year by rabies. 95% of which are Africa and Asia. Because rabies has no human-to-human transmission, the priority of countermeasures against infectious diseases tends to be lower. Rabies virus infects all mammals, wild animals are the source of human infection. You have some background information on rabies. Now let's look at the focus of Pasteur's research. Research Question Is it possible to create a rabies vaccine? Methods and Data In 1831, Pasteur conducted an experiment. 1. He got Joseph Meister bitten by a rabid dog inoculated with inactivated rabies virus as a vaccine. 2. Meister was vaccinated for 11 days and escaped the onset. 3. This was the first successful example. Conclusions and Future Research He called vaccination the process from infection to immunity. This is the etymology of vaccine. Thanks to the experiment of Pasteur, now rabies has become an infectious disease that can prevent onset.