It depends on the sentence.To figure out which is right, take away "you." If you would say "I," then use "you and I." If you would say "me," then use "you and me." However, many native speakers get this "wrong." You'll here people who always say "you and me" no matter what. And then you will meet people who got corrected a lot in school for that, so they always say "you and I" even when "me" would be right.This is one of those areas where you can learn to speaker better than a native. :-) Examples: You and I should go to a movie before summer's over. Anna is going to come with you and me instead of her parents.

It depends on the sentence! Tell us the sentence you want to say, and we'll tell you which is the right word to use. Basically, the rule is this: You use 'I' if 'you and I' is the subject of the sentence : like the nominative case in German. For example, 'You and I both understand the problem.' You use 'me' if 'you and me' is the object of the sentence: like the accusative or dative cases in German. For example 'This is a difficult time for you and me.'

"You and I" is used for more formal situations, like writing a letter or talking to someone important. For all other occasions, it's fine to use "You and me" Either is fine in conversation, but 'you and me' is most common.

Me and u