For the second one, you could say something like: "The party is located / takes place in my house (now)." So it kinda makes sense, I imagine that you had a party going on on the streets and continue it at your house now. The first one is almost impossible - the translation would still be: The shop is at the end of the road, but not with the "is" like in "The book is on the table", but like the one in "The sky is blue", it's a descriptive "is". Does this make sense? :)