presentation background Background Hello, my name is Koya Tanzaki, and today I would like to talk about first chemotherapy and the developers. The early 20th century, the European people who were going to go to Africa were troubled by terrible local disease. The sleepy sickness in Africa is one of those local disease. Paul Ehrich though there were pigment to attach only at the bacteria which invaded the body, and to sterilize. This is another key person. Kiyoshi Shiga, foreign student from Japan, came over to labo in Germany. Shiga studied a sampling method of Shigella in pupils of Kitasato which was a famous bacteriological researcher. Paul decided to study an effective pigment agent with Shiga. At first, he ordered the animal experiment using the mouse to Shiga. The sleepy sickness in Africa is infected a person by a fly. Patients distracted and fall into a coma, and finally die by trypanosome which is a pathogen. So Kiyoshi decided to look for a pigment to specifically spoil trypanosome. You have some background information on trypanosome. Now let’s look at focus of theirs research.