Basically, they have the same meaning, and they are often used in one sentence: "Hogyne, persze!" There is only a slight difference between the two words. Let me show it through grammar and some examples: Hogyne! /Hogy (how) + ne (not)/ <-Denial in it - Can you help me? - Hogyne! = Of course, how could I not help you?! Persze! <- Affirmative - Can you help me? - Persze! = Of course I can. I hope the above helps. :)