You would have to be more specific I'm afraid, context would help. However generally "to do" means something a specific person has done or could do, and is the past tense. "to make" is to craft something out of ingredients or components. You always need components or ingredients to make something, where as anyone can do something

Sometimes do and make can be used for the same thing. The big difference between them is to make means to create where to do is an action you are taking. For example- you would say "I am going make dinner" you would not say "I am going to do dinner" Hope this helps!