입니까 is Hapsyo-che It is used between strangers at the start of a conversation among male co-workers by TV announcers to customers 이세요 is Haeyo-che It is used mainly in Korean phrasebooks for foreigners between strangers, especially those older or of equal age between female co-workers or friends by younger speakers as a less old-fashioned alternative to the hao-che. by men and women in Seoul as a less formal alternative to the hapsyo-che. In fact, There are more variations with the honorific suffix -시-. 이십니까 and 입니까 이세요 and 이에요. High level of formality for listener 그는 학생입니까? 저 분은 선생님이십니까? (Express honorific for the subject) Middle level of formality for listener 그는 학생이에요? 저 분은 선생님이세요? (Express honorific for the subject) Low level of formality for listener 그는 학생이야? 저 분은 선생님이셔?. (Express honorific for the subject) Refer to https://en.wikipedia.org/wiki/Korean_speech_levels