If you are transcribing a doctor's notes, it reads like the first sentence is the history, and the second is his or her diagnosis of the patient's problem. While the shared use of "metastases" indicates a connection, as Michael stated earlier, there is no clear connection without more words or context. As to "different chemotherapies," it is unclear as well. Do you mean different sessions (weekly, monthly, etc.) of the same chemotherapy, or different types (of treatment, as in different medications or chemicals) of chemotherapy? I hope this helps you, Jonathan.

"Underlying sclerotic bony metastases." looks incomplete, like explaining about computers in the first part then saying, "Internal wiring of the circuits.". Doesn't look right in one or two sentences since there is no clear connection between the two. I would elaborate on the second part.