How can we orient usselt in the best way?

What is the best way for us to prepare ourselves for the future?

[While you are using the verb "to orient" properly, these days it is used most often in the expression "get yourself/myself oriented". Ex. A driver gets into a new car and say, "Give me a minute so I can get myself oriented." Or in the adjective, "disoriented" meaning "somewhat confused". A similar expression is "get yourself/myself situated". If you want to say, "set yourself up for success" the verb "prepare" may be better.]

I'm in my last year/senior year at university. 

[Last year of high school or university is the "senior year".]

But so far I haven't yet found an answer which I felt really satisfiable.

But I have yet to find a satisfying answer?

This is not only my problem but also the problem of many students now. [Good]

I and my friends in the same class still ask each other some questions such as :

I, along with my friends in the same class, still ask each other questions like:

" What would you do after you graduated? or would you work with your major? "

"What will you do after you graduate? Or will you be able to find work in your major [or in your field]?"

[You could also say, "What are you going to do after you graduate?"]

And I am usually recieved an answer : " I don't know".

Usually their answer is, "I don't know."

It's so sad when we can't orient usself.

It's so sad when you can't get yourself oriented. 

[To use more common phrases, you could say, "It's so sad when you feel disoriented in life."

Maybe we are affected by the many opinions from of our family and by our social life. [Good.]

Those things made us find usself in the difficult way. 

Those things make it difficult for you to find yourself.

So what can we do to find what's necessary for usself?

So what do we need to do in order to find ourselves?

[or "How can we prepare ourselves for the future?" The phrase "in order" is like "để"]]