They can be used to mean the same thing. Also, "house" means the building itself. "Home" also means the place the family lives. In America, we have a saying "Home is where the heart is" that means the building itself does not make it home, but the family does. I hope that helps more than it confuses.

House is fangzi, home is ni jia

A house is a physical building. A home is your idea of where you live (which can include a building of course!).

Most people consider house means home. Precisely, they are different. In United States, all citizens are secure at home. The law enforcement persnnel (police) can not enter your home without search warrant. If you live in a mobil home, then the mobile home is your home. If you live in a boat, the boat is your home. Home is where the people who live and sleep there. Definition by law: it must have four walls and a roof. House is a structure which can be make in any shape. Most people live and sleep in a house, therefore, house and home means the same. But, if you are going to argue in court. The definition of house and home is different.

House is a building, Home place surrounded by the ones you love