Ciao; we don't need to capitalize all the first letters at all. At least, in Italy; and surely for such a long title. HOwEvEr you might always consider the graphic design factor, which unchains you from writing all the same font, all the same size, all the same capitalization and color.. you know, it soon gives the idea of the topic -- and the target public. Besides, in my humble opinion, I'd use the Capitalization to underline the key words >> Forty Days in Italy con *La Mia Famiglia: How to research your Italian roots and travel to Italy on your own terms (Do you use to capitalize after the column, don't you? but you might consider to write the second part as detached explanation, on its own, smaller font. Best