I agree with Simon about 1 & 2. For number 3, "career" is possible, but are you sure you mean "career "and not "job"? A career can involve a number of jobs, not just one. Don't forget to begin your sentences with capital letters.

1. what annoys you about your job r your estudies? what annoys you the most: your job or you studies ? (although using "annoying" here sounds weird) 2. in your job or studies, is there anything you are not happy? in (about / concerning / when you think about) your job or your studies, is there anything you are not happy with? 3. when you imagine the perfect career , what do you think of? when you imagine the perfect career , what can you see? 4. what keeps you awake at night?

1. What annoys you about your job or your studies? 2. In your job or studies, is there anything you are not happy with? Las otras frases son correctas :)