Son diferentes modos de decir lo mismo.

Thank you all for your responses, appreciate it! :)

is the same meaning "mucho gusto" but the first is more formal and the second one "encantada de conocerte" is more emotional

Let me try to translate the two phrases: 1. "mucho gusto" -> "nice to meet you" 2. "Encantada de conocerte" -> "glad to meet you" I use the first one in any situation when I meet new people. But the second is when I meet personaly someone who I'd interested to meet, I mean someone from whom I heard. I actually refer to a personal emotion of being glad

Si, es verdad que tienen el mismo significado...pero yo utilizo más a menudo encantada de conocerte porque suena más natural y a la vez formal. :)