Hi Mariana :) To isolate means to get or to keep something by itself. For example, we often talk about isolating patients in a hospital when they have a very contagious disease. To insulate means to protect something from the effects of what is around it, usually by surrounding it with something protective. This word most often refers to temperature. For example, we talk about insulating your house to keep it warm in the winter. And there are insulated containers to keep food hot or to keep drinks cold. I hope that helps!