House refers to the building, the "thing". Home refers to the familiar, the place where you live, or where your family is. Where you belong.

I think Aline said it best :) Some examples of "house" and "home" : "I want to go home." "Welcome to our home!" "What a nice home you have." "Let's go to my house." "We're selling our house." "They are building a house." "What a nice house you have." Another thing to mention is that all of the 'house' sentences can be replaced with 'home' and still make sense, but they sound less natural and give the sentences a slightly different meaning.

Another way to think of it is... an empty house, is just a house, a building but not a home. An inhabited house is a home for it's inhabitants.

house is used especially for home that consists ground floor and one ore more upper floors. home is the place where someone live permanently, it could be flat or house or villa. ..... may other one explain better.