I'm pissed off with everything, means I am annoyed with everything. If you won some money and accidently dropped it in a river, you'd be, "pissed off". "Piss" (vulgar) is a word for urinate. We use vulgarities in colloquial language, "I'm pissed off, I'm fucked off" - "I wish he would just piss off" - "I wish he would fuck off". But they are vulgar terms and they must never be used in any polite conversation or business situation. I might - well I would say it to my brother. To be pissed off with everything simply means you are sick/fed up/had enough/annoyed with/tired of everything. You have no enthusiasm/spirit or energy for anything in that moment.

Thanks for all of your helping:))))

i'm angry with everything

-"piss off" is an idiom,when it's a verb means like "go away" -"i'm pissed off everything"= i'm annoyed with everything (in this case,"pissed off" used as an adjective means "annoyed/depressed...") All the best! :o)

im angry with everything