'notwithstanding" is not common and I wouldn't recommend its use. However, one way to use it not mentioned (and still uncommon) would be to place it as in the following: His good looks notwithstanding, he's never had luck finding love. His legal problems notwithstanding, he's always been shrewd at identifying profitable business opportunities. Note that you can't use "despite" this way.

'Notwithstanding means 'despite'. It's not commonly used. Notwithstanding their youth and inexperience, the team won the championship. Notwithstanding her age, she's in perfect health.

understood*

Thanks for your addition, too Rea

thanks jonathan I understood it very well.