We normally say "do you mind if...?" However, you could say, "Will I disturb you if I open the window?" "Do I disturb you if I open the window?" sounds as if you frequently open the window, but have only now wondered if it disturbs the other person.

Will is better and funnier. Like others said, mind is the word in this case.

Do you mind if I open the window?

I'd say it's correct, however, i think English native speakers would say most likely: "Do you mind if I open the window?" or "Does it bother you if I open the window" （"it" here refers to the action - to open the window) or “You don't mind I open the window, Do you?"

You know.