ABSTRACT 2 Social programs are intended to generate growth and reduce the poverty of indigenous or rural communities to promote socioeconomic development. However, there are programs that may not achieve their objectives due to poor planning and design of development strategies. The present work is a case study with respect to the community of Rincon de los Pirules, State of Mexico, whose objective is the design of a strategy for sustainable socioeconomic development (EDSES) based on a local phytogenetic resource focused on a Mazahua community . For such case, a socioeconomic diagnosis was made with statistical information of the community, an environmental diagnosis on the state of conservation of the forest on which the community depends, determining the conservation of dead wood and a classification of groups of users of plant genetic resources. from knowledge of plant genetic resources, ethnic identity and traditional knowledge. The results showed that Rincon de los Pirules is a community with a high degree of marginalization that lacks local employment sources. The forest area is in a favorable state of conservation; However, there is an absence of dead wood due to the collection of firewood for fuel in Mazahua homes. Six groups of users of plant genetic resources were identified for the design of the EDSES for the Mazahua population. The strategy was formulated from squash (Cucurbita sp.) And cempasuchil (Tagetes sp.) As popular crops for users because of the interest for commercial production that supports the creation of local employment sources. This main action is complemented with the collection of perlilla stick (Symphoricarpos sp.) And the cultivation of gladiola (Gladiolus sp.) For the elaboration of crafts and flower arrangements. The degree of traditional knowledge and ethnic identity incorporated in the conservation of the forest and the orientation in the use of plant genetic resources are fundamental for the design of the EDSES in native communities. Keywords: exploitation, strategy, rural development, plant resources Thank you very much for your help.