Announcement manuscript of a study Back ground Hello my name is KY ,and I`d like to talk about Sinya Yamanaka and his work to create the first the Ipscells. In 1981 ,while the study to regenerate the organ lost by sickness and an injury is performed. The EScells which is one of stem cells is developed. And that was expected regenerative medicine of an incurable disease. But it was possible to get EScells from only an embryo in an occurrence early stage. So danger is exerted on a mother`s body and fertilized egg which should be a child is broken ,and each country government could write now regulation on a EScells research work. To evade such problem Yamanaka making the Ipscells from a cell of mouse in 2006 ,a human skin cell in 2007. Research Question Can the organ regenerate by own cells.