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Is this correct? I´ve been doing a course in Coursera about Clinical Research. I wrote in the Discussion Forum and I wanted to know if there is any mistake. I'm sorry if this is a heavy topic "In the case of Mr. Ryan I really think he should have received the experimental drug. The evidence for the superiority of PLX4032 was too strong and it seems that there was not a clinical equipoise. Besides they were not honest since the beginning with what they knew about the established drug and the experimental drug, at least it was what I understood from this article. There is a recent case in Brazil where a drug that supposedly cures cancer was being given to patients without ever having a clinical study. There was only some studies in vitro and with animals. This drug was given to patients for years and when the authorities realized that and stopped the distribution, a lot of patients demanded the access to the compound saying it has worked on them. I know that the distribution of the drug was prohibited and now they are doing the phase II of clinical research and it seems like the drug it is not as miraculous as people believed. This drug gave false hopes for the patients and a lot of patients died using this pill without ever contributing to the understanding of this drug"

Corrections · 7

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Is this correct?

I´ve been doing a course in Coursera about Clinical Research. I wrote in the Discussion Forum and I wanted to know if there are any mistakes. I'm sorry if this is a heavy topic

"In the case of Mr. Ryan I really think he should have received the experimental drug. The evidence for the superiority of PLX4032 was too strong and it seems that there was not a clinical equilibrium*. Besides, they were not honest since the beginning with what they knew about the established drug and the experimental drug. At least this is how I understood the article.

There is a recent case in Brazil where a drug, supposedly cancer curing, was being given to patients with no clinical study. There were only some studies in vitro and on animals. The drug had been given to patients for years and when the authorities realized this and stopped its distribution, many patients demanded continuing access to the compound saying it had worked for them.

I know that the distribution of the drug was prohibited and now they are doing the phase II of clinical research and it seems like the drug it is not as miraculous as people had believed. This drug gave false hopes for the patients and a lot of patients died using this pill without ever contributing to the understanding of this drug"

*not quite sure about 'clinical equilibrium, or, equipoise' ?!

Very well written!

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Thank you, John! I had not even noticed this
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Don't use the ´ accent acute symbols. Use the ' apostroph symbol. It's a bad habit that will later bite you, when you wonder why some software does not recognize your input (for example when you fill out forms online or like online exams, etc.)
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Thanks, Bia! This helps me very very much. I often use stats and am puzzled by the clinical trials jargon. Now I can find out precisely what they mean. Coursera is a good, dependable site, too.
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it's the course Design and Interpretation of Clinical Trials, by Johns Hopkins University https://www.coursera.org/learn/clinical-trials

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