What keeps us healthy and happy as we go through life? A recent TED talk given by Robert Waldinger discussing a 75 years long study by Harvard University, aiming to find the key factor of having a good life. The research group tracked life of more than hundreds of young people. Some of them were graduates from Harvard and the rest were teenagers from Boston, especially from families with problems. They were interviewed and asked questions about their work, home life and health status year on year. Some dropped out the study and some still are alive and actively participate the survey. People in study group have experienced quite different lives with diverse occupations while commonality still be found towards forming a good life. The lesson generated from this study is simple and clear. Good relationship keeps us healthier and happier. 1.Social connections are good for us. People are more socially connected with family, friends and communities are more happier. Loneliness are toxic that killing us. 2.Instead of quantity, quality of close relationship matters. Good close relationship can even buffer the physical pain we will suffer at 80-90s as time goes by. 3.Good relationship protect both our body and brain. The possibility of memory decline decreased. In summary, a good life is built with good relationships.