Hey there, I guess it would all depend on the context. If you had a business website in Spain and your point was to communicate that your company can conduct business in Spanish or English I think I would just say "We speak English". Or "Our services are available in English or Spanish".

Hi Shawn! I wanted to know if saying "Talk business in english" is correct? for example... Talk business english like a tittle in a website... does it sound good?

Anabel, it sounds like you are asking for the informal expression or slang.. For instance: Let's talk shop. Let's get down to business. Business before pleasure.