Summary In his article "On Beyond 100" published in the National Geographic Magazine, Stephen S. Hall gives us clues about the importance our genes might have on the road to longevity, to disease-free old age. The article talks about how, for example, in a small village in Calabria, Italy, a geneticist and a geriatrician investigate the secret of the longevity of many of its inhabitants. They have discovered that although they have been consumers of a diet with very few calories, possibly there is a genetic component linked to their longevity, which comes to demystify the fact that the secret of a long life is only in food. Stephen Hall explains how the scientific community is already focusing on genetic research thanks to medical advances. Above all, in small isolated populations where the main component is good health in old age. For example, in Ecuador, there is a population where there are more cases of a genetic mutation that causes growth problems and that adults look like children, is the so-called Laron syndrome. However, it is proving that this mutation could protect them from diseases as important as cancer or diabetes.