Alzheimer's: The Silent Plague In most studies about Alzheimer's scientists have noticed that protein deposits can be found between neurons interfering the synapse's process. Basically the debate about this neurodegenerative disease has been focused on two proteins: Tau and Amyloid proteins. As a part of cell skeleton tauproteins are responsible for the stability within nerve cells. But in patients with Alzheimer's this protein is defective, producing uncontrolled fiber bundles which interfere the exchange of communication between axons. It seems that these missfolded neurofibrillary tangles take the nerve cell's stability and block a healthy activity in synapse. Experts don't know exactly about the factors which may lead to tauprotein's mutations. Therefore they try to develop medicines which can act as an inhibitor, intercepting the grow of defective tauproteins. Despite intensive scientific research the exact mechanism and function of tauprotein continues to be hardly understood.