White Matter fibers Studying through Fiber Tracking in MRI 2
(PART 2)
The component tissue of White Matter which is the principal responsible of the water molecules Anisotropic Diffusion is not the myelin, but the membrane cell. In case of alteration structure of axonal tracks the Anisotropic Value reduces. DWI technique has only a feeling for movement which has the same direction of the gradient. For this it represent a limit for Myelinated fibers study. Fiber Tracking is a technique for improving the graphic representation and interpretation of Brain Molecules Imaging Diffusion dates, through 3D reconstruction of Axonal Tracks’s Central Nervous System.
Fiber Tracking brief two information’s type :
- Quantitative Valuation of Anisotropic Grade
- Axonal Fiber’s Spatial Orientation
Fiber Tracking tries to identify with major clarity the structure of brain fibers. The fibers are obtained by following voxel to voxel ( with specific algorithm ) the major Diffusion of Water Molecules. Whole technique finishes with the overlapping of the 3D Axon tracks Technique and the MRI Morphological Images. Fiber Tracking can be obtained by following two methods: Deterministic Method and Stochastic Method.
Deterministic Method permits to make good images also with low SNR because it has a small number of images weighted Diffusion. The elaboration time is short, permitting the methodic compatible with the clinical routine. This method is operator-dependent because the operator must has great anatomic knowledge. Instead Stochastic Method needs big number of images weighted Diffusion obtaining an accurate evaluation of the probability orientation of the fibers in the area. This methods is not operator-dependent but the elaboration time is long. In addition 3T MRI Scanners permit to obtain images with major spatial resolution ( thank to the higher SNR) e to make functional images. With 3T MRI scanners is possible to increase B-Value , permitting to study smaller axonal tracks or with windy ways.
The role of Radiographer is important for positioning of the patient, acquisition and elaboration of the images.
The Fiber Tracking is used for :
- Encephalic pathology
- Studying cerebral connectivity
- Studying Cerebral Ischemia, Pathology of White Matter, Neurochirurgic Planning, Neurodegenerative Diseases.
In conclusion major advantages of Fiber Tracking are about tumor resection . It permits to have minor invasivity , minor postoperative complications, major cost-benefit rapport during Intracranial Tumor Sugery.
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